Released in 2003, Ophidian: 2350 is a collectible card game (CCG) created by Ophidian Games and Fleer. It uses a play structure called the Flow rather than the normal turn-based system typically used in the genre.
Ophidian 2350 takes place in the year 2350, where a strange reptilian race known as Ophidians run gladitorial arenas for humans, aliens and demons alike. Combat consists of one team pitted against another, and though competitors often die, the gladiators' DNA is often taken before the match to resurrect the fallen warrior.
Each player's team is made up of up to four gladiators, usually one of each victory point (VP) level (ranging from 1 to 4), but a team can technically be made up of any combination that adds up to 10. A player can win either by defeating an opponent's gladiators, by defeating gladiators worth a greater number of victory points after four waves (rounds) or by amassing 15 points worth of cheer from the audience.